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July 18, 2023

Unveiling the Power of Diagnostic Imaging in Early Disease Detection

Diagnostic imaging uses various technologies and techniques to create a visual representation of the internal mechanisms and components of the human body. It helps doctors diagnose, monitor, and treat various diseases and conditions, such as cancer, heart disease, stroke, infection, injury, etc. Imaging also helps patients to prevent or decrease the likelihood of problems and boost their quality of life.

However, diagnostic imaging is not only helpful in confirming or ruling out a diagnosis but also for detecting diseases at an early stage before they can cause any symptoms or signs. Early detection is crucial for improving the chances of survival and recovery, reducing the cost and burden of treatment. It also helps to prevent the spread of diseases and protect public health.

In this article, we will explore how diagnostic imaging can unveil the power of early disease detection and also discuss the benefits and challenges of using diagnostic imaging for this purpose. We will also look into some of the recent developments in diagnostic imaging technologies and techniques.


A brief overview of diagnostic imaging

Diagnostic imaging uses different physical principles and properties to capture images of different parts of the body. For this, a variety of tools are used such as electromagnetic radiation, sound waves, magnetic fields, radio waves, radioactive substances, etc. Depending on the type and purpose of the examination, different diagnostic imaging technologies and techniques are used to create images of different parts or systems of the body, such as bones, organs, tissues, blood vessels, nerves, etc.

Some of the most popular diagnostic imaging examinations are:

  • X-ray – electromagnetic radiation that can penetrate tissues and organs and create images based on the different absorption rates of different structures.
  • Ultrasound sound waves bounce off tissues and organs and create images based on the different reflection rates of different structures. It can detect foetal development, heart function, kidney stones, etc.
  • CT scan – creates cross-sectional images of the body based on the different attenuation rates of different structures. CT scans are commonly used to detect lung cancer, liver cirrhosis, appendicitis, etc.
  • MRI – uses magnetic fields and radio waves that can interact with hydrogen atoms in the body and create images based on the different resonance rates of different structures. They can find brain tumours, spinal cord injuries, multiple sclerosis, etc.
  • Positron emission tomography (PET) – radioactive substances are injected into the body. They emit positrons detectable by a scanner. This is used to build images based on the various metabolic rates of different structures. PET can detect Alzheimer’s disease, Parkinson’s disease, lymphoma, etc.

These examinations use different physical principles and properties to capture images of the body that are not visible to the naked eye. These images provide detailed and accurate information about the anatomy and physiology of the body and identify any abnormalities or changes which could be a sign of an illness or its development.

Diagnostic imaging provides a range of benefits to patients, doctors, and society. Some of these benefits include improved chances of survival and recovery, reduction in the cost of treatment, enhanced quality of life, and transmission prevention. Some challenges, such as limited access, variable quality, potential harm, and ethical issues, need to be addressed when using imaging.

The world of diagnostic imaging is going through continuous improvement, thus meeting the needs of the healthcare system and society. Some of these advancements include molecular imaging, and wearable devices.

Malaysia is home to some of the most advanced imaging technologies in Asia across medical specialities, including cardiology, gynaecology, oncology, and orthopaedics. This is one of the reasons why it is a leading global healthcare destination.


Early disease detection

As the name suggests, early detection is the process of diagnosing a disease at its initial stages. It is crucial for improving patients’ prognosis and quality of life. It can be extremely useful for certain serious diseases such as cancer. Detection at an early stage can help prognosis immensely and improve the chances of recovery.

Our article about the Importance of Early Detection in Cancer Treatment will help you gain a better understanding of early detection of cancer.

Benefits of early disease detection

Improved survival and recovery

Early disease detection can improve the survival and recovery outcomes of patients who suffer from otherwise fatal or debilitating diseases if left untreated or diagnosed late.

Reduced cost and burden

Detecting a disease early can reduce the cost and burden of treatment for patients, doctors, and society. It helps avoid unnecessary or invasive procedures or therapies that may have adverse effects or complications.

Enhanced quality of life

Early disease detection can enhance the quality of life for patients who suffer from diseases that may affect their physical, mental, or social well-being. Detecting diseases helps prevent or alleviate symptoms or signs that may impair their function or comfort.

Prevented transmission

One more benefit of using imaging for early disease detection is that it can prevent the transmission of diseases that may spread to other people or animals. Detecting diseases as early as possible can help identify and isolate infectious diseases that may pose a public health threat.


Early disease detection and diagnostic imaging

Diagnostic imaging is one of the main ways of detecting a disease at its initial stages. Let us take the example of three important types of diagnostic imaging and understand how they can help in early detection of a disease.

CT Scan

CT scans produce finely detailed cross-sectional pictures of the body using X-rays. CT scans can reveal abnormalities that physical examination or blood tests do not show. These abnormalities can include tumours, infections, fractures, blood clots, and other conditions in different parts of the body.

It can also provide information about the disease’s location, size, shape, and extent. For example, CT scans can detect lung cancer early by showing small nodules or masses. CT scans can also guide biopsy or other procedures to obtain tissue samples for diagnosis. Furthermore, it can monitor the response to treatment or the progression of the disease by showing changes in the size or appearance of the lesions.

However, CT scans also have some limitations and risks.

  • One of the main drawbacks of scans is radiation exposure, which can damage cells and increase cancer risk. The amount of radiation depends on the type and duration of the scan. However, in general, early diagnosis offers advantages that outweigh the risks of radiation exposure.
  • Another limitation of CT scans is the possible allergic reactions or side effects caused by contrast agents or tracers that are sometimes used to enhance the visibility of particular structures or functions.
  • These substances may cause nausea, vomiting, itching, rash, or difficulty breathing in some people. These reactions are usually mild and treatable, but rarely, they may be severe or life-threatening.
  • A third limitation of CT scans is the cost and availability of the technique. Scans may be expensive and might not be accessible or covered by insurance in all healthcare settings. It also requires specialised equipment and personnel that may not be accessible in rural or low-resource areas.

MRI

Radio waves and a high magnetic field are used in Magnetic Resonance Imaging to provide clear images of soft tissues, organs, bones, and blood vessels. MRI can provide more information than CT scans for some diseases, especially those affecting the brain, spinal cord, nerves, muscles, joints, and breasts. It can also show how different tissues and organs function by measuring their metabolic activity.

For example, MRI can detect Alzheimer’s disease early by showing brain structure or function changes. It can also diagnose multiple sclerosis by showing damage to the brain’s and spinal cord’s white matter. MRI can also guide biopsy or other procedures to obtain tissue samples for diagnosis. Moreover, it can monitor the response to treatment or the progression of the disease by showing changes in tissue characteristics or activity.

However, MRI also has some limitations and risks.

  • One of the main drawbacks of MRI is that it cannot be used for people with metal implants or devices in their body, such as pacemakers, cochlear implants, or artificial joints. The magnetic field can interfere with these devices causing damage or malfunction.
  • Another drawback is that patient movement or breathing can cause motion artefacts to interfere with it. It can reduce the quality and accuracy of the images.
  • A third limitation of MRI is the cost and availability of the technique. It is more expensive than CT scans and might not be accessible or covered by insurance in all healthcare settings.
  • MRI also requires specialised equipment and personnel that may not be accessible in rural or low-resource areas.

X-rays

X-rays make images of bones, lungs, hearts, and other structures using electromagnetic energy. It can show bone changes, such as fractures, arthritis, or osteoporosis. X-rays can also show lung changes such as pneumonia, tuberculosis, or lung cancer.

It can also show heart size or shape changes due to heart failure or congenital disabilities.

For example, X-rays can detect tuberculosis early by showing lung cavities or calcifications. X-rays can also diagnose lung cancer by showing masses or nodules in the lungs.

However, X-rays also have some limitations and risks. One of the main drawbacks of X-rays is that they cannot provide detailed information about soft tissues, organs, or blood vessels. Additionally, X-rays miss small or subtle abnormalities that CT scans or MRIs may be able to pick up.

Another limitation of X-rays is radiation exposure, which can damage cells and increase cancer risk. The amount of radiation depends on the scan’s type and duration, but early detection generally has more significant advantages than dangerous radiation exposure.

Some people also develop allergic reactions or side effects caused by contrast agents or tracers that are sometimes used to enhance the visibility of specific structures or functions. These substances may cause nausea, vomiting, itching, rash, or difficulty breathing. These reactions are usually mild and treatable, but occasionally, they may develop into something severe.


Advancements in the world of diagnostic imaging

Diagnostic imaging technologies and techniques are continually changing and improving to fulfil the needs and challenges of global healthcare systems.

Let us take a look at some of these advancements:

Molecular imaging

Molecular imaging uses substances that bind to specific molecules or cells in the body and emit signals that a scanner can detect and create images based on molecular or cellular activity. Molecular imaging can improve diagnostic imaging by providing more detailed and functional information about the biology and pathology of diseases.

For example, according to a study by Science Translational Medicine, molecular imaging can detect prostate cancer from urine samples with high sensitivity and specificity.

Wearable devices

Wearable technology refers to any gadget attached to the body to measure or monitor various physiological parameters or functions, such as heart rate, blood pressure, glucose level, etc. These devices can supplement diagnostic imaging by providing continuous and real-time data indicating changes or abnormalities in the body.

For example, according to a study by Nature Biomedical Engineering, wearable devices can detect atrial fibrillation from electrocardiograms with high accuracy and reliability.


Wrapping-up

Diagnostic imaging is a powerful tool that can unveil the power of early disease detection by providing images of the internal structures and functions of the body that are not visible to the naked eye. Early disease detection is crucial for improving the chances of survival and recovery and reducing the cost and burden of treatment. Early disease detection can also help prevent disease spread and protect public health.

Diagnostic imaging is one of the main methods to detect a disease early. Hence, advancements in this field will benefit Medical Science, irrespective of the branch of medicine.



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